Nauka innov. 2007, 3(2):51–62
https://doi.org/10.15407/scin3.02.051

В. Ye. Paton1, D. M. Kaleko1, K. V. Lyapina1, T. V. Melnichenko1, B. O. Movchan1, O. O. Moibenko2, Yu. V. Panichkin3, A. G. Portnichenko2, S. V. Salo3, L. V. Tumanovska2, A. I. Ustinov1, M. Ya. Yuzkiv2
1Ye.O. Paton Electric Welding Institute, NAS of Ukraine, Kyiv
2O.O. Bogomoletz Institute of Physiology, NAS of Ukraine, Kyiv
3M.M. Amosov Institute of Cardiovascular Surgery, Kyiv

 

Development and Biological Testing of Domestic Vascular Prosthetic Stents for Treatment of Heart Vessels and Other Organs

Section: R&D Projects of "Program of Cooperation between National Academy of Sciences of Ukraine  and Kyiv City State Administration"
Language: Ukrainian
Abstract: New stents having porous surface for filling with medication have been developed. Surface has extra rigidity in radial direction and sufficient flexibility in longitudinal direction. Corvitin developed in A. A. Bogomoletz Institute of Physiology of NASU is offered as filler
Key words: stents, coronary vessels, ischemic disease, electron beam technology, porous surface, corvitin.

References:
1. Knyshev G. V., Furkalo S. N., Panichkin Ju. V., Berestovenko V. S. Jendovaskuljarnoe protezirovanie venechnyh arterij. Ukr. kardiologichnij zh-l. 1998, No 7–8: 5–12 [in Russian].
2. Wieneke H., Dirsch O., Sawitowski T., Gu Y. L., Brauer H., Dahmen U., Fischer A., Wnendt S., Erbel R. Synergistic effects of a novel nanoporous stent coating and tacrolimus on intima proliferation in rabbits. // Catheter Cardiovasc Interv. – 2003 Nov. – 60(3). – S. 399–407.
3. Phan T. T., See P., Tran E., Nguyen T. T., Chan S. Y., Lee S. T., Huynh H. Suppression of insulin-like growth factor signalling pathway and collagen expression in keloid-derived fibroblasts by quercetin: its therapeutic potential use in the treatment and/or prevention of keloids. // Br. J. Dermatol. – 2003 Mar. – Vol. 148(3). – S. 544–552.
4. Pawlikowska-Pawlega B., Gawron A. Effect of quercetin on the growth of mouse fibroblast cells in vitro. // Pol. J. Pharmacol. – 1995 Nov-Dec. – 47(6). – S. 531–535.
5. Kandaswami C., Perkins E., Drzewiecki G., Soloniuk D. S., Middleton E. Jr. Differential inhibition of proliferation of human squamous cell carcinoma, gliosarcoma and embryonic fibroblast-like lung cells in culture by plant flavonoids. // Anticancer Drugs. – 1992 Oct. – 3(5). – S. 525–530.
6. Zava D. T., Duwe G. Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro. // Nutr. Cancer. – 1997. – 27(1). – S. 31–40.
7. Hofmann J., Doppler W., Jakob A., Maly K., Posch L., Uberall F., Grunicke H. H. Enhancement of the antiproliferative effect of cis-diamminedichloroplatinum(II) and nitrogen mustard by inhibitors of protein kinase C. // Int. J. Cancer. – 1988 Sep. – 15; 42(3). – S. 382–8.
8. Weber G., Shen F., Prajda N., Yang H., LiW., Yeh A., Csokay B., Olah E., Look K. Y. Regulation of the signal transduction program by drugs. Adv. Enzyme Regul. – 1997. – 37. – S. 35–55.
9. Csokay B., Prajda N., Weber G., Olah E. Molecular mechanisms in the antiproliferative action of quercetin. // Life Sci. – 1997. – 60(24). – S. 2157–63.
10. Phan T. T., Sun L., Bay B. H., Chan S. Y., Lee S. T. Dietary compounds inhibit proliferation and contraction of keloid and hypertrophic scar-derived fibroblasts in vitro: therapeutic implication for excessive scarring. // J. Trauma. – 2003 Jun. – 54(6). – S. 1212–24.
11. Gaspardone A., Versaci F., Tomai F., Citone C., Proietti I., Gioffre G., Skossyreva O. C-Reactive Protein, Clinical Outcome, and Restenosis Rates After Implantation of Different Drug-Eluting Stents. // Am. J. Cardiol. – 2006 May. – 1; 97(9). – S. 1311–1316.
12. Newell M. C., Henry C. R., Sigakis C. J., Unger B. T., Larson D. M., Chavez I. J., Burke M. N., Traverse J. H., Henry T. D. Comparison of Safety and Efficacy of Sirolimus-Eluting Stents Versus Bare Metal Stents in Patients With ST-Segment Elevation Myocardial Infarction. // Am. J. Cardiol. – 2006 May. – 1; 97(9). – S. 1299–1302.
13. Parry T. J., Brosius R., Thyagarajan R., Carter D., Argentieri D., Falotico R., Siekierka J. Drug eluting stents: sirolimus and paclitaxel differentially affect cultured cells and injured arteries. // Eur J. Pharmacol. – 2005 Nov. – 7; 524 (1–3). – S. 19–29.
14. Patent Rossijskoj Federacii N 2016659. Sposob lechenija ostrogo infarkta miokarda i nestabil'noj stenokardii. Parhomenko A. N., Mojbenko A. A., Kolchin Ju. N. i dr [in Russian].
15. Curcio A., Torella D., Cuda G., Coppola C., Faniello M. C., Achille F., Russo V. G., Chiariello M., Indolfi C. Effect Of Stent Coating Alone On In Vitro Vascular Smooth Muscle Cell Proliferation and Apoptosis. // Am. J. Physiol. Heart Circ Physiol. – 2003 Oct. – 30.
16. Movchan B. A. Neorganicheskie materialy osazhdennye iz parovoj fazy v vakuume. Sovremennoe materialovedenie 21 veka. Kyiv: Nauk. dumka, 1998: 318–332 [in Russian].
17. Ustinov A. I., Ljapina K. V., Mel'nichenko T. V. Zakonomernosti formirovanija poristoj struktury nerzhavejushhej stali pri ee osazhdenii iz parovoj fazy v prisutstvii parov hloristogo natrija. Sovremennaja jelektrometallurgija. 2005, No 4: 23–28 [in Russian].
18. Paton B. Je., Kaleko D. M., Panichkin Ju. V., Salo S. V. Trubchasta detal', shho rozshyrjujet'sja, dlja intraljuminal'noi' opory (stenta) ta intraljuminal'na opora. Patent Ukrai'ny na vynahid N76013. Zajavl. 19.07.2004, op. 15.06.2006 (bjul.N6) [in Ukrainian].